- Eaddy
- Eade
- Eads
- Eagar
- Eagon
- Eakin
- Earthman
- Easley
- Eason
- East
- Easter
- Easterly
- Eastwood
- Eaton
- Ebbets
- Eblen
- Eckert
- Eckhart
- Eddins
- Eddlemon
- Edens
- Edmondson
- Edmunds
- Edwards
- Eells
- Egulf
- Ehman
- Eichhorn
- Eicholtz
- Eickholt
- Eidson
- Einstein
- Eisen
- Eisert
- Elberry
- Elbert
- Elder
- Eldridge
- Elgin
- Elkins
- Ellingham
- Elliott
- Ellis
- Elliston
- Ellithorpe
- Ellzy
- Elmer
- Elmore
- Elrod
- Elshtain
- Elson
- Elton
- Elver
- Emberton
- Emery
- Emory
- Endo
- Endres
- Engelhardt
- England
- Englert
- English
- Ensey
- Ensley
- Entrekin
- Epps
- Erickson
- Ericson
- Ernsberger
- Ernst
- Ervin
- Eskew
- Eskind
- Eslick
- Esmon
- Essig
- Estes
- Etheridge
- Ethridge
- Etta
- Etter
- Eubank
- Eubanks
- Eva
- Evans
- Everett
- Everton
- Evetts
- Ewell
- Ewin
- Ewing
- Exelbert
- Ezell
- Ezzell